Penn Medicine has broken ground for a forthcoming $270 million outpatient center at 200 DeKalb Pike in North Wales (Montgomeryville), the nonprofit health system announced last week.

The 162,000 sf multispecialty outpatient facility is expected to open in late 2027 and “will expand options for patients to receive advanced care in Montgomery and Bucks counties”, the announcement said.

It will also provide comprehensive cancer care, including radiation oncology services and chemotherapy, primary care, heart and vascular, orthopaedic and neuroscience care, and specialized services in women’s health and surgical consultations.

“By bringing advanced, lifesaving services closer to patients, especially those undergoing cancer therapy that can last for months, we’re not just enhancing accessibility—we’re transforming the entire treatment journey,” said Kevin B. Mahoney, CEO of the University of Pennsylvania Health System. “Penn Medicine Montgomeryville will make getting care easier for patients, while reimagining how treatments should be delivered and experienced.”

Other Penn Medicine multispecialty ambulatory sites include: in Philadelphia, the Perelman Center for Advanced Medicine, Penn Medicine University City, and Washington Square; elsewhere in Pennsylvania, facilities in Bucks County, Radnor, Valley Forge, Southern Chester County (West Grove), and Lancaster County; and in New Jersey, locations in Cherry Hill, Mount Laurel, and Woodbury Heights.

Rendering: Penn Medicine